The NBN founder mutation-Evidence for a country specific difference in age at cancer manifestation.
Krystyna H ChrzanowskaEva SeemanovaRaymonda VaronMartin DigweedDorota Piekutowska-AbramczukKarl SperlingPavel SeemanPublished in: Cancer reports (Hoboken, N.J.) (2022)
It is reasonable to assume that this finding also sheds light on the higher cancer risk of NBN heterozygotes in CS than in Poland. This has implications for genetic counseling and individualized medicine also of probands with other DNA repair defects.