Bile acid alterations characterize the early onset and progression of nonalcoholic fatty liver disease in young mice fed with high fat and fructose diet.

We found the enterohepatic circulation of BAs changed and progressed along with the development of NAFLD, and the younger mice might be more susceptible to an unhealthy diet. HCA and LCA species are potential biomarkers for predicting and evaluating the development of NAFLD. This article is protected by copyright. All rights reserved.