Efficacy of perineural versus intravenous dexmedetomidine as a peripheral nerve block adjunct: a systematic review.

Nasir HussainChad M BrummettRichard BrullYousef AlghothaniKenneth MoranTamara SawyerFaraj W W Abdallah

Published in: Regional anesthesia and pain medicine (2021)

Moderate quality evidence appears to suggest that intravenous dexmedetomidine is an inferior peripheral nerve block adjunct compared with perineural dexmedetomidine. Perineural dexmedetomidine is associated with longer durations and faster onset of sensory and motor blockade.

Keyphrases

cardiac surgery
high dose
acute kidney injury
high intensity
chemotherapy induced
low dose