Identifying high-risk neurological phenotypes in adult-onset classic monogenic autoinflammatory diseases: when should neurologists consider testing?

Guilherme Diogo da Silva João Vitor MahlerSérgio Roberto Pereira da Silva JuniorLeonardo Oliveira MendonçaPedro Lucas Grangeiro de Sá Barreto Lima Paulo Ribeiro Nóbrega Fernando Kok Fernando Freua

Published in: BMC neurology (2024)

Neurologists should be proactive in diagnosing monogenic autoinflammatory diseases in young adults showcasing clinical and laboratory indications of inflammation, especially when symptoms align with recurrent or chronic meningitis, small vessel disease strokes, and demyelinating lesions.

Keyphrases

young adults
oxidative stress
cerebrospinal fluid
subarachnoid hemorrhage
cerebral ischemia