Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography.
Ulrike LöbelNils Daniel ForkertPeter SchmittThorsten DohrmannMaria SchroederTim MagnusStefan KlugeChristina Weiler-NormannXiaoming BiJens FiehlerJan SedlacikPublished in: PloS one (2016)
In contrast to conventional MRI, almost all patients showed pathological changes in cerebral hemodynamics assessed by SWI and 4D MRA. Loss of venous contrast on SWI is most likely the result of an increase in CBF and may be related to the acute onset of anemia. Future studies will be needed to assess a possible therapeutic effect of blood transfusions in patients with HUS and neurological symptoms.
Keyphrases
- contrast enhanced
- magnetic resonance
- magnetic resonance imaging
- computed tomography
- end stage renal disease
- chronic kidney disease
- subarachnoid hemorrhage
- diffusion weighted imaging
- ejection fraction
- newly diagnosed
- cerebral ischemia
- optical coherence tomography
- prognostic factors
- peritoneal dialysis
- patient reported outcomes
- depressive symptoms
- respiratory failure
- brain injury
- aortic dissection
- case report
- fluorescence imaging
- cerebral blood flow
- mechanical ventilation