Pharmacokinetics of asundexian with combined CYP3A and P-gp inhibitors and an inducer: Target in vitro and in vivo studies.

Friederike KanefendtChristine BraseNatalia JungmannRobert FrickeAnna EngelenSebastian Schmitz

Published in: British journal of clinical pharmacology (2023)

The presented studies confirmed that CYP3A4 and P-gp contribute to asundexian metabolism and excretion. Observed effects were in line with data from a previous mass balance study.

Keyphrases

case control
machine learning
deep learning
data analysis