The galanin receptor-3 antagonist, SNAP 37889, inhibits cue-induced reinstatement of alcohol-seeking and increases c-Fos expression in the nucleus accumbens shell of alcohol-preferring rats.

Kira-Elise WilsonSigrid LimburgMelissa K DugganAdam J LawtherSpencer J WilliamsAndrew J LawrenceMatthew W HaleElvan Djouma

Published in: Journal of psychopharmacology (Oxford, England) (2018)

These data support previous findings of galanin-3 receptor involvement in cue-induced reinstatement of alcohol-seeking behaviour, and provide novel evidence that the ability of galanin-3 receptor antagonism to attenuate cue-induced reinstatement relates to activation of the nucleus accumbens shell.

Keyphrases

high glucose
diabetic rats
mental health
drug induced
oxidative stress
endothelial cells
big data
stress induced