Increased habenular connectivity in opioid users is associated with an α5 subunit nicotinic receptor genetic variant.

Kaylah CurtisHumsini ViswanathKenia M VelasquezDavid L MolfeseMark J HardingEduardo AramayoPhilip R BaldwinElisa AmbrosiAlok MadanMichelle PatriquinB Christopher FruehJ Christopher FowlerThomas R KostenDavid A NielsenRamiro Salas

Published in: The American journal on addictions (2017)

Our data uncovered a promising brain target for development of novel anti-addiction therapies and may help the development of personalized therapies against opioid abuse. (Am J Addict 2017;26:751-759).

Keyphrases

chronic pain
pain management
resting state

white matter
electronic health record
genome wide

big data
copy number
blood brain barrier

deep learning
brain injury