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Oxidized SOD1 accelerates cellular senescence in neural stem cells.

Teng GuanYing GuoTing ZhouQiang YuJingyi SunBaoliang SunGuohui ZhangJiming Kong
Published in: Stem cell research & therapy (2024)
Oxidized hSOD1 is a causal factor in the cellular senescence of NSCs. The removal of oxidized hSOD1 is a strategy to rejuvenate NSCs and to improve the quality of EVs derived from senescent cells.
Keyphrases
  • low density lipoprotein
  • neural stem cells
  • induced apoptosis
  • dna damage
  • endothelial cells
  • cell cycle arrest
  • stress induced
  • quality improvement
  • oxidative stress
  • signaling pathway
  • cell death
  • cell proliferation