Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease secondary to IL-10 receptor deficiency.
Natascha Silva SandyLia Furlaneto MaregaGiane Dantas BecharaAdriana Gut Lopes RiccettoCarmem Maria Sales BonfimMaria Marluce Dos Santos VilelaAntonio Fernando RibeiroMaria de Fatima ServidoniElizete Aparecida LomaziPublished in: Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo (2021)
Our case reports disclose novel findings on plasma cytokine profile in IL-10R deficiency, and we describe the severe phenotype of IL-10/IL-10R deficiency that should be recognized by physicians.