Mitochondria-targeted combination treatment strategy counteracts myocardial reperfusion injury of aged rats by modulating autophagy and inflammatory response.
Behnaz MokhtariReza BadalzadehPublished in: Molecular biology reports (2023)
and mitochondrial transplantation attenuated myocardial I/R injury in aged rats, in part by modulating autophagy and inflammatory response, hence, appears to restore aging-related loss of cardioprotection in aged patients.
Keyphrases
- inflammatory response
- signaling pathway
- cell death
- oxidative stress
- end stage renal disease
- lipopolysaccharide induced
- left ventricular
- endoplasmic reticulum stress
- ejection fraction
- chronic kidney disease
- newly diagnosed
- lps induced
- toll like receptor
- prognostic factors
- immune response
- stem cells
- cancer therapy
- patient reported outcomes
- acute coronary syndrome
- mesenchymal stem cells
- subarachnoid hemorrhage