miR-125a-3p regulates apoptosis by suppressing TMBIM4 in lens epithelial cells.

Lihua KangJiawei LuoPengfei LiGuowei ZhangMiao WeiMin JiHuaijin Guan

Published in: International ophthalmology (2022)

This study indicated that miR-125a-3p regulated apoptosis by suppressing TMBIM4 in LECs under oxidative damage, providing a new idea for clinical therapeutic target of cataract.

Keyphrases

oxidative stress
endoplasmic reticulum stress
cell cycle arrest
cell death
transcription factor
cataract surgery
signaling pathway