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Kinetic Modelling of Infection Tracers [18F]FDG, [68Ga]Ga-Citrate, [11C]Methionine, and [11C]Donepezil in a Porcine Osteomyelitis Model.

Lars JødalSvend B JensenOle L NielsenPia AfzeliusPer BorghammerAage K O AlstrupSøren B Hansen
Published in: Contrast media & molecular imaging (2017)
The kinetics of the four studied tracers in infection was characterized. For clinical applications, [18F]FDG remains the first-choice PET tracer. [11C]methionine may have a potential for detecting soft tissue infections. [68Ga]Ga-citrate and [11C]donepezil were not found useful for imaging of osteomyelitis.
Keyphrases
  • pet ct
  • positron emission tomography
  • soft tissue
  • high resolution
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  • human health
  • decision making
  • fluorescence imaging