The prevalence of lynch syndrome (DNA mismatch repair protein deficiency) in patients with primary localized prostate cancer using immunohistochemistry screening.
Suguru OkaShinji UrakamiKiichi HagiwaraMichikata HayashidaKazushige SakaguchiYuji MiuraNaoko InoshitaMasami AraiPublished in: Hereditary cancer in clinical practice (2023)
In this study, immunohistochemical screening of MMR proteins for Lynch syndrome was performed in a series of prostate cancer cases. The prevalence of Lynch syndrome in localized prostate cancer was 0.8%, which is low compared with other Lynch syndrome-associated cancers.