ALKBH5 promotes lung fibroblast activation and silica-induced pulmonary fibrosis through miR-320a-3p and FOXM1.
Wenqing SunYan LiDongyu MaYi LiuQi XuDemin ChengGuanru LiChunhui NiPublished in: Cellular & molecular biology letters (2022)
Our findings suggest that ALKBH5 promotes silica-induced lung fibrosis via the miR-320a-3p/FOXM1 axis or targeting FOXM1 directly. Approaches aimed at ALKBH5 may be efficacious in treating lung fibrosis.