Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes.

Felix StaderMarco SiccardiManuel BattegayHannah KinvigMelissa A PennyCatia Marzolini

Published in: Clinical pharmacokinetics (2020)

The developed repository for aging subjects provides a singular specific source for key system parameters needed for physiologically based pharmacokinetic modeling and can in turn be used to investigate drug kinetics and drug-drug interaction magnitudes in the elderly.

Keyphrases

adverse drug
drug induced
emergency department
community dwelling
electronic health record