Login / Signup

Two new benzophenones from endohydric moss Polytrichum Commune.

Xu-Hong DuanJian-Cheng ZhaoLin LiLin PeiPei HeRong Wang
Published in: Natural product research (2018)
Two new benzophenones (1 and 2), were isolated from the endohydric moss Polytrichum commune. Their structures were elucidated by spectroscopic methods including extensive 2 D NMR techniques. Compound 2 is the first example of benzophenone with a rare cyclopropylacetamide from the natural resources. Compounds 1 and 2 were screened their cytotoxicity against five cancer cell lines (HCT-116, A-549, MCF-7, HepG2, A-375,), and no cytotoxic activities were observed (IC50 > 100 μM).
Keyphrases
  • high resolution
  • papillary thyroid
  • magnetic resonance
  • molecular docking
  • squamous cell
  • breast cancer cells
  • lymph node metastasis
  • cell cycle arrest
  • mass spectrometry
  • cell death
  • signaling pathway