PmrAB, the two-component system of Acinetobacter baumannii , controls the phosphoethanolamine modification of lipooligosaccharide in response to metal ions.
Noriteru YamadaGo KamoshidaTsukasa ShiraishiDaiki YamaguchiMomoko MatsuokaReika YamauchiNana KandaRoku KamiokaNorihiko TakemotoYuji MoritaMasahiro FujimuroShin-Ichi YokotaKinnosuke YahiroPublished in: Journal of bacteriology (2024)
as well as its biological functions. Understanding the molecular biology of these molecules, which serve as drug resistance factors and are involved in environmental recognition mechanisms in bacteria, is crucial for developing fundamental solutions to the AMR problem.