Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing.

Aiichiro NagakiKengo SasatsukiSatoshi IshiuchiNobuyuki MiuchiMasahiro TakumiJun-Ichi Yoshida

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2019)

Synthesis of ketones containing various functional groups from acid chlorides bearing electrophilic functional groups and functionalized organolithiums was achieved using a flow microreactor system. Extremely fast mixing is important for high chemoselectivity.

Keyphrases

quantum dots
molecularly imprinted
mass spectrometry
capillary electrophoresis
liquid chromatography