Myocardial Blood Flow Reserve, Microvascular Coronary Health, and Myocardial Remodeling in Patients With Aortic Stenosis.
Fares AlahdabAhmed Ibrahim AhmedMalek NayfehYushui HanOla AbdelkarimMoath Said AlfawaraStephen H LittleMichael J ReardonNadeen N FazaSachin S GoelMohamad Adnan AlkhouliWilliam A ZoghbiMouaz H Al MallahPublished in: Journal of the American Heart Association (2024)
Despite lack of ischemia, as severity of AS increased, MFR decreased and GLS worsened, reflecting worse coronary microvascular health and myocardial remodeling. Positron emission tomography-derived MFR showed a significant independent correlation with left ventricular ejection fraction and GLS. Patients with prosthetic aortic valve showed a high prevalence of impaired MFR.
Keyphrases
- aortic stenosis
- left ventricular
- ejection fraction
- aortic valve
- positron emission tomography
- blood flow
- aortic valve replacement
- transcatheter aortic valve implantation
- transcatheter aortic valve replacement
- computed tomography
- public health
- healthcare
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- heart failure
- acute myocardial infarction
- left atrial
- mitral valve
- coronary artery disease
- mental health
- health information
- pet ct
- health promotion
- pet imaging
- coronary artery
- human health
- percutaneous coronary intervention
- atrial fibrillation