Previous BCG vaccination is associated with less severe clinical progression of COVID-19.
Susan Martins PereiraFlorisneide Rodrigues BarretoRamon Andrade de SouzaCarlos Antonio de Souza Teles SantosMarcos Pereira SantosEnny Santos da PaixãoCarla Cristina Oliveira de Jesus LimaMarcio Santos da NatividadeAna Angélica Bulcão Portela LindosoEder Gatti FernandesEvonio Barros Campelo JuniorJulia Moreira PescariniKaio Vinicius Freitas de AndradeFernanda Mattos de SouzaElisangela Alves de BrittoCeuci NunesMaria Yuri IchiharaMargareth DalcolmoAnete TrajmanManoel Barral-NettoIbrahim AbubakarMauricio Lima BarretoRicardo Arraes de Alencar XimenesLaura Cunha RodriguesPublished in: BMC medicine (2023)
This protection may be relevant for public health in settings where COVID-19 vaccine coverage is still low and may have implications for research to identify vaccine candidates for COVID-19 that are broadly protective against mortality from future variants. Further research into the immunomodulatory effects of BCG may inform COVID-19 therapeutic research.