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Molecular MR-Imaging for Noninvasive Quantification of the Anti-Inflammatory Effect of Targeting Interleukin-1β in a Mouse Model of Aortic Aneurysm.

Julia BrangschCarolin ReimannJan Ole KaufmannLisa Christine AdamsDavid OnthankChrista Thöne-ReinekeSimon RobinsonMarco WilkeMichael WellerRebecca BuchholzUwe KarstRene BotnarBernd HammMarcus Richard Makowski
Published in: Molecular imaging (2021)
Molecular-MRI enables the early visualization and quantification of the anti-inflammatory-effects of an IL-1β-inhibitor in a mouse-model of AAAs. Responders and non-responders could be identified early after the initiation of the therapy using molecular-MRI.
Keyphrases
  • mouse model
  • contrast enhanced
  • magnetic resonance imaging
  • aortic aneurysm
  • anti inflammatory
  • single molecule
  • computed tomography
  • diffusion weighted imaging