Local Electrical Dyssynchrony during Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results.
Pawel KuklikBenjamin SchäfferBoris A HoffmannAnand N GanesanDoreen SchreiberJulia M MoserRuken Ö AkbulakArian SultanDaniel StevenBart MaesenUlrich SchottenChristian MeyerStephan WillemsPublished in: PloS one (2016)
Local electrical dyssynchrony provides a reasonable estimator of regional AF complexity defined as the number of fibrillatory waves. Additionally, it points to regions of dynamical instability related with action potential alternans. However, despite those characteristics, its utility in guiding catheter ablation of AF is limited suggesting other factors are responsible for AF persistence.
Keyphrases
- atrial fibrillation
- catheter ablation
- left atrial
- left atrial appendage
- oral anticoagulants
- left ventricular
- direct oral anticoagulants
- heart failure
- cardiac resynchronization therapy
- percutaneous coronary intervention
- density functional theory
- coronary artery disease
- mitral valve
- acute coronary syndrome
- venous thromboembolism
- drug induced