Microglial and astrocytic responses in the human midcingulate cortex in Huntington's disease.
Thulani PalpagamaAimee Rose MillsMackenzie Wendy FergusonPraju Vikas AnkealClinton TurnerLynette TippettBert van der WerfHenry John WaldvogelRichard Lewis Maxwell FaullAndrea KwakowskyPublished in: Annals of neurology (2023)
This study presents pathological changes in microglia and astrocytes in the midcingulate cortex in Huntington's disease, which coincide with mood symptom presentation. These findings further the understanding of neuroinflammation in Huntington's disease, a necessary step for developing inflammation-targeted therapeutics. This article is protected by copyright. All rights reserved.