Hippocampal neural cell degeneration and memory deficit in high-fat diet-induced postnatal obese rats- exploring the comparable benefits of choline and DHA or environmental enrichment.
Gayathri S PrabhuMohandas K G RaoKiranmai Sesappa RaiPublished in: The International journal of neuroscience (2020)
High fat diet-induced postnatal obesity in rats causes CA1/CA3 hippocampal neuro-degeneration and memory deficits. Supplementation of choline and DHA in obese rats attenuates these deficits.
Keyphrases
- high fat diet induced
- insulin resistance
- adipose tissue
- metabolic syndrome
- weight loss
- type diabetes
- traumatic brain injury
- preterm infants
- working memory
- obese patients
- skeletal muscle
- single cell
- cell therapy
- bariatric surgery
- stem cells
- cerebral ischemia
- body mass index
- brain injury
- protein kinase
- physical activity
- temporal lobe epilepsy
- weight gain
- blood brain barrier