Flow Cytometry-Based Measurement of Antibodies Specific for Cell Surface-Expressed Folded SARS-CoV-2 Receptor-Binding Domains.

Al Nasar Ahmed SehgalJera SafranBernhard Kratzer Pia GattingerRobert B StiegerLaszlo MusiejovskyDoris TrapinPaul EttelUlrike KörmöcziArno RottalKristina BorochovaYulia DorofeevaInna TulaevaMilena WeberKatharina Grabmeier-PfistershammerThomas PerkmannUrsula WiedermannRudolf ValentaWinfried F Pickl

Published in: Vaccines (2024)

We have established a toolbox for measuring SARS-CoV-2-specific immunity against cell-bound virus antigens, which may be considered as an important addition to the armamentarium of SARS-CoV-2-specific diagnostic tests, allowing flexible and quick adaptation to new variants of concern.

Keyphrases

sars cov
flow cytometry
respiratory syndrome coronavirus
cell surface
single cell
stem cells
coronavirus disease
transcription factor
solid state