Single-nucleotide polymorphisms in 3'-untranslated region inducible costimulator gene and the important roles of miRNA in alopecia areata.

Giuseppina ConteducaA RossiF MegiorniA ParodiF FerreraS TarditoT AltosoleV FaustiC OccellaF KalliS NegriniA PizzutiC MarcheseE RizzaF IndiveriD CovielloD FenoglioGilberto Filaci

Published in: Skin health and disease (2021)

Our data show that rs4404254 and rs4675379 SNPs of ICOS gene are associated with AA and also reveal that the presence of rs4404254 polymorphism correlates with ICOS post-transcriptional repression by microRNA binding.

Keyphrases

genome wide
copy number
dna methylation
genome wide identification
gene expression
transcription factor
electronic health record
big data
machine learning
artificial intelligence
oxidative stress
heat shock
heat stress
genome wide analysis
data analysis
heat shock protein