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Mechanism-based inhibition of CYP3A subfamilies by macrolide antibiotics and piperine.
Toshiro Niwa
Risa Ishii
Published in:
Drug metabolism and bioanalysis letters (2022)
It is speculated that the preincubation-dependent inhibition by piperine would be more potent in CYP3A5 non-expressors than CYP3A5-expressors.
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