Discovery and Validation of a Volatile Signature of Eosinophilic Airway Inflammation in Asthma.

Rosa PeltriniRebecca L CordellMichael WildeShahd AbuhelalEleanor QuekNazanin Zounemat-KermaniWadah IbrahimMatthew RichardsonPaul BrinkmanFlorence SchleichPierre-Hugues StefanutoHnin AungNeil GreeningSven Erik DahlenRatko DjukanovicIssssswan M AdcockChristopher BrightlingPaul MonksSalman Siddiqui

Published in: American journal of respiratory and critical care medicine (2024)

We have discovered and provided early-stage clinical validation of a volatile biomarker signature associated with eosinophilic airway inflammation. Further work is needed to translate our discovery using point of care clinical sensors.

Keyphrases

early stage
small molecule
high throughput
chronic obstructive pulmonary disease
squamous cell carcinoma
lung function
allergic rhinitis
low cost
neoadjuvant chemotherapy
sentinel lymph node
rectal cancer