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A Small Molecule TrkB Neurotrophin Receptor Partial Agonist as Possible Treatment for Experimental Nonarteritic Anterior Ischemic Optic Neuropathy.

Mohammad Ali ShariatiVarun KumarTao YangChandrani ChakrabortyBen Anthony BarresFrank Michael LongoYaping Joyce Liao
Published in: Current eye research (2018)
AION: anterior ischemic optic neuropathy, BDNF: Brain-derived neurotrophic factor, GCC: ganglion cell complex, MAP: mitogen-activated protein, OCT: spectral-domain optical coherence tomography, OD: right eye, ON: optic nerve, ONH: optic nerve head, OS: left eye, RGC: retinal ganglion cell; Trk: tropomyosin kinase.
Keyphrases
  • optic nerve
  • optical coherence tomography
  • small molecule
  • single cell
  • diabetic retinopathy
  • cell therapy
  • cerebral ischemia
  • brain injury
  • protein protein
  • neuropathic pain
  • blood brain barrier