Type distribution of human papillomaviruses in ThinPrep cytology samples and HPV16/18 E6 gene variations in FFPE cervical cancer specimens in Fars province, Iran.
Ali FarhadiHaniyeh AbueiMohammad Ali OkhovatBita GeramizadehAbbas Behzad BehbahaniPei Pei ChongNegin NikouyanSepide NamdariPublished in: Cancer cell international (2023)
The present study suggests that the prevalence of HPV infection in women of all age groups with or without premalignant lesions in the southwestern Iran is high and the predominant HPV types in the southwest of Iran may differ from those detected in other parts of the country. This study also highlights the necessity of not only initiating HPV vaccination for the general population but also developing new vaccines that confer immunity against the prevalent HPV types in the area and national cervical screening programs using a combination of thinPrep cytology test and HPV detection assays in order to improve the accuracy of the screening.
Keyphrases
- high grade
- cervical cancer screening
- fine needle aspiration
- endothelial cells
- gene expression
- public health
- metabolic syndrome
- type diabetes
- pregnant women
- copy number
- south africa
- adipose tissue
- insulin resistance
- dna methylation
- transcription factor
- quantum dots
- loop mediated isothermal amplification
- genome wide identification