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Cardiorespiratory responses to muscle metaboreflex activation in fibrosing interstitial lung disease.

Charlotte ChenJohn KolbeMargaret L WilsherSally De BoerJulian F R PatonJames P Fisher
Published in: Experimental physiology (2022)
, P = 0.596). At the end of PECO, dyspnoea ratings in FILD were similar to controls (1.0 ± 1.3 units vs. 0.5 ± 1.1 units). Exercise increased MAP and HR (P < 0.05) in both groups; however, responses were lower in FILD. Collectively, these findings suggest that there is not an augmented effect of the muscle metaboreflex on breathing and dyspnoea in FILD, but haemodynamic responses to handgrip are reduced relative to controls.
Keyphrases
  • interstitial lung disease
  • systemic sclerosis
  • rheumatoid arthritis
  • skeletal muscle
  • idiopathic pulmonary fibrosis
  • high intensity
  • resistance training