Combined Effects of the FSHR 2039 A/G and FSHR -29 G/A Polymorphisms on Male Reproductive Parameters.

Rossella Cannarella Nicolò Musso Rosita Angela CondorelliMarco MusmeciStefania Stefani Sandro La Vignera Aldo Eugenio Calogero

Published in: The world journal of men's health (2020)

The SNPs FSHR 2039 A/G and FSHR -29 G/A in combination did not seem to have any effect on male reproductive function in a cohort of Sicilian men. The effect of these SNPs has only been studied in granulosa cells so far. Further studies on their role in Sertoli cells are needed.

Keyphrases

induced apoptosis
cell cycle arrest
genome wide
endoplasmic reticulum stress
oxidative stress
gene expression
cell death
metabolic syndrome
adipose tissue
insulin resistance