In vivo tumour imaging employing regional delivery of novel gallium radiolabelled polymer composites.
Ross W StephensGregory D TredwellJessica L BellKaren J KnoxLee A PhilipTim J SendenMichael J TapnerStephanie A BickleyMarcel R TanudjiStephen K JonesPublished in: Biomaterials research (2021)
This method of producing 67Ga-radiolabelled polymer microspheres is suitable for SPECT-CT imaging of the regional vascular delivery of microspheres to tumour sites in animal models. Sharper distinction of model tumours from normal liver was obtained with smaller MS, and tumour resolution may be further improved by the use of 68Ga instead of 67Ga, to enable PET imaging.