Minor DNA methylation changes are observed in spermatozoa prepared using different protocols.
Martin StimpfelEda Vrtacnik-BokalPublished in: Andrology (2020)
Although the average genome-wide level of sperm DNA methylation was similar in both sample groups, a distinctive number of methylation changes were observed in DMR and DMP levels. A larger number of samples should be analyzed and additional sperm preparation methods should be tested to confirm our findings.