Acidic Microenvironment-Sensitive Core-Shell Microcubes: The Self-assembled and the Therapeutic Effects for Caries Prevention.
Tsai-Miao ShihJui-Fu HsiaoDar-Bin ShiehGuochuan Emil TsaiPublished in: European journal of dentistry (2022)
In our study, an intelligent toothpaste was developed that selectively inhibits cariogenic bacteria by microenvironment proton-triggered fluoride release. Such novel design would accomplish a favorable flora balance for optimal long-term oral health.