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Olmesartan-associated Enteropathy with Acute Kidney Injury.

Moo Jin KangKyung Hwa MinHyung Wook KimSu Bum ParkDae Hwan KangCheol Woong ChoiSu Jin KimHyeong Seok NamDae Gon Ryu
Published in: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi (2022)
Olmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the exclusion of coeliac disease, as it mimics coeliac sprue. Once diagnosed, it can be completely cured with the discontinuation of olmesartan. However, due to the extremely low incidence of OAE in Korea, clinical suspicion and diagnosis may be a challenge. The authors report the first case of OAE presenting with chronic diarrhea and acute kidney injury in Korea.
Keyphrases
  • drug induced
  • angiotensin ii
  • liver injury
  • acute kidney injury
  • small bowel
  • angiotensin converting enzyme
  • blood pressure
  • vascular smooth muscle cells
  • risk factors
  • case report
  • adverse drug
  • electronic health record