In utero exposure to alloantigens primes alloimmunization to platelet transfusion in mice.

Jacqueline N PostonArijita JashLindsay M HannanAriel M HayChomkan UsaneerungruengHeather L HowieLinda M KappJames C Zimring

Published in: Transfusion (2020)

These findings isolate antecedent pregnancy as a causal contribution to increased frequencies of alloimmunization by subsequent platelet transfusion in mice and provide a platform for ongoing mechanistic investigation.

Keyphrases

sickle cell disease
high fat diet induced
cardiac surgery
high throughput
preterm birth
acute kidney injury
wild type
pregnancy outcomes