Intralesional interferon alpha-2b as a novel treatment for periocular squamous cell carcinoma in horses.

Brittany B MartabanoSteven DowLyndah ChowMargaret M V WilliamsMaura K MackRebecca BelloneKathryn L Wotman

Published in: PloS one (2024)

Perilesional administration of IFNα2b was found to be well-tolerated in horses with PSCC, and induced tumor regression in 42% of treated eyes. Treatment failure appears unrelated to the development of IFNα2b antibodies.

Keyphrases

squamous cell carcinoma
dendritic cells
immune response
optical coherence tomography
radiation therapy
oxidative stress
combination therapy
lymph node metastasis
newly diagnosed
replacement therapy