Mycobacterium avium Subspecies paratuberculosis Infects and Replicates within Human Monocyte-Derived Dendritic Cells.

William D Rees Ana Cecilia Lorenzo-LealTheodore S SteinerHoracio Bach

Published in: Microorganisms (2020)

Infection and subsequent proliferation of MAP within moDCs could provide a unique means for the dissemination of MAP to lymphoid tissue, while altering immune responses to facilitate the persistence of infection of host tissues in CD.

Keyphrases

dendritic cells
immune response
endothelial cells
regulatory t cells
mycobacterium tuberculosis
gene expression
high density
signaling pathway
toll like receptor
nk cells