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Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease.

Ignacio Illán-GalaAlberto LleoAnna KarydasAdam M StaffaroniHenrik ZetterbergRajeev SivasankaranLea T GrinbergSalvatore SpinaJoel H KramerEliana M RamosGiovanni CoppolaRenaud La JoieGil D RabinoviciDavid C PerryMaria Luisa Gorno-TempiniWilliam W SeeleyBruce L MillerHoward J RosenKaj BlennowAdam L BoxerJulio C Rojas
Published in: Neurology (2020)
This study provides Class III evidence that plasma NfL has superior diagnostic and prognostic performance vs plasma t-tau in FTLD and AD.
Keyphrases
  • cerebrospinal fluid
  • mild cognitive impairment