Differences in Predicted Warfarin Dosing Requirements Between Hmong and East Asians Using Genotype-Based Dosing Algorithms.

Boguang SunYa-Feng WenKathleen A Culhane-PeraMuaj LoTxia XiongKoobmeej LeeKerui PengBharat ThyagarajanJeffrey R BishopHeather A Zierhut Robert J Straka

Published in: Pharmacotherapy (2020)

The unique allele frequencies related to warfarin when combined with nongenetic factors observed in the Hmong translate into clinically relevant differences in predicted maintenance dose requirements for Hmong versus East Asians.

Keyphrases

atrial fibrillation
venous thromboembolism
direct oral anticoagulants
machine learning
oral anticoagulants
deep learning
drug induced