The role of damage control surgery in the treatment of perforated colonic diverticulitis: a systematic review and meta-analysis.
Roberto CirocchiGeorgi PopivanovMarina KonaktchievaSonia ChipevaGuglielmo TellanAndrea MingoliMauro ZagoMassimo ChiarugiGian Andrea BindaReinhold KafkaGabriele AnaniaAnnibale DoniniRiccardo NascimbeniMohammed EdilbeSorena AfsharPublished in: International journal of colorectal disease (2020)
The present meta-analysis revealed an approximately 62.1% weighted rate of achieving GI continuity with the DCS approach to generalized peritonitis in Hinchey III and IV with major leaks of 4.7% and overall mortality of 9.2%. Despite the promising results, we are aware of the limitations related to the significant heterogeneity of inclusion criteria. Importantly, the low rate of reported septic shock may point toward selection bias. Further studies are needed to evaluate the clinical advantages and cost-effectiveness of the DCS approach.
Keyphrases
- septic shock
- systematic review
- case control
- single cell
- minimally invasive
- magnetic resonance
- coronary artery bypass
- meta analyses
- cardiovascular events
- oxidative stress
- risk factors
- magnetic resonance imaging
- type diabetes
- cardiovascular disease
- combination therapy
- coronary artery disease
- network analysis
- percutaneous coronary intervention
- replacement therapy