Early dynamics of circulating tumor DNA predict clinical response to immune checkpoint inhibitors in metastatic renal cell carcinoma.

Yoko KohKosuke NakanoKotoe KatayamaGaku YamamichiSatoru YumibaEisuke TomiyamaMakoto MatsushitaYujiro HayashiYoshiyuki YamamotoTaigo KatoKoji HatanoAtsunari KawashimaTakeshi UjikeRyoichi ImamuraRui YamaguchiSeiya ImotoYukimasa ShiotsuNorio NonomuraMotohide Uemura

Published in: International journal of urology : official journal of the Japanese Urological Association (2022)

Our findings revealed that early circulating tumor deoxyribonucleic acid dynamics can serve as a predictive biomarker for response to immune checkpoint inhibitors in metastatic renal cell carcinoma patients.

Keyphrases

circulating tumor
metastatic renal cell carcinoma
cell free
circulating tumor cells
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
single cell