Extracellular vesicle microRNA cargo is correlated with HPV status in oropharyngeal carcinoma.

Ben PeacockAlice RigbyJames R Bradford Ryan Charles Pink Keith David Hunter Daniel W Lambert Stuart Hunt

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

Here, we identify EV miRNA signatures indicative of the HPV status of the parent cell. This may provide a platform from which to validate salivary or blood-based biomarkers with utility for early detection and stratifying risk in OPSCC patients.

Keyphrases

end stage renal disease
high grade
ejection fraction
newly diagnosed
chronic kidney disease
single cell
prognostic factors
stem cells
cell therapy
gene expression
genome wide
mesenchymal stem cells