Extracellular vesicle microRNA cargo is correlated with HPV status in oropharyngeal carcinoma.
Ben PeacockAlice RigbyJames R BradfordRyan Charles PinkKeith David HunterDaniel W LambertStuart HuntPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)
Here, we identify EV miRNA signatures indicative of the HPV status of the parent cell. This may provide a platform from which to validate salivary or blood-based biomarkers with utility for early detection and stratifying risk in OPSCC patients.