Regioselective 1,4-/1,3-Difunctionalization of 1,3-Enynes with Selenosulfonates in Water.

Hong-He DengShi-Yin TianJia-Hui HanXin-Yu LiuWei-Dong RaoShu-Su ShenDaopeng ShengZhao-Ying YangShun-Yi Wang

Published in: The Journal of organic chemistry (2024)

1,4-/1,3-Regioselective bifunctionalization of 1,3-enynes with selenosulfonates in water under catalyst-free conditions for the construction of sulfonyl allene and 1,3-disulfonyl-conjugated dienes respectively have been developed. The reactions feature mild reaction conditions in aqueous solution and remarkable regioselectivity controlled by substrates.

Keyphrases

aqueous solution
machine learning
photodynamic therapy
ionic liquid
deep learning
room temperature
highly efficient