DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.
Xinyan HuFangfang LiYulan ZhouHairun GanTian-Cheng WangLuting LiHaoyu LongBing LiPengfei PangPublished in: Cancer medicine (2022)
DDX24 acted as a pro-tumorigenic factor and promoted metastasis in NSCLC. DDX24 interacted with RPL5 to promote its ubiquitination and degradation. As a result, targeting DDX24/RPL5 axis may provide a novel potential therapeutic strategy for NSCLC.