Actigraphic Correlates of Neuropsychiatric Symptoms in Adults with Focal Epilepsy.

Together, these results demonstrate that RAR features may encode prevalent depression and anxiety symptoms in patients with focal epilepsy, potentially offering wearable-derived endpoints to adjunct clinical care and drug/device trials. With larger PWE-specific actigraphic-psychometric datasets, we may identify RAR signatures that may more precisely correlate with varying seizure frequency, the burden of anticonvulsant therapy and prevalent mood/anxiety symptoms.