Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study.
Cloé DomenighettiPierre-Emmanuel SugierAshwin Ashok Kumar SreelathaClaudia SchulteSandeep GroverOcéane MohamedBerta PortugalPatrick MayDheeraj Reddy BobbiliMilena Radivojkov-BlagojevicPeter LichtnerAndrew B SingletonDena G HernandezConnor EdsallGeorge D MellickAlexander ZimprichWalter PirkerEkaterina RogaevaAnthony E LangSulev KoksPille TabaSuzanne LesageAlexis BriceJean-Christophe CorvolMarie-Christine Chartier-HarlinEugénie MutezKathrin BrockmanAngela B DeutschländerGeorges M HadjigeorgiouEfthimos DardiotisLeonidas StefanisAthina Maria SimitsiEnza Maria ValenteSimona PetrucciStefano DugaLetizia StranieroAnna ZecchinelliGianni PezzoliLaura BrighinaCarlo FerrareseGrazia AnnesiAndrea QuattroneMonica GagliardiHirotaka MatsuoYusuke KawamuraNobutaka HattoriKenya NishiokaSun Ju ChungYun Joong KimPierre KolberBart P C van de WarrenburgBastiaan R BloemJan AaslyMathias ToftLasse PihlstrømLeonor Correia GuedesJoaquim J FerreiraSoraya BardienJonathan CarrEduardo TolosaMario EzquerraPau PastorMonica Diez-FairenKarin WirdefeldtNancy L PedersenCaroline RanAndrea C BelinAndreas PuschmannClara HellbergCarl E ClarkeKaren E MorrisonManuela M X TanDimitri KraincLena F BurbullaMatt J FarrerRejko KrügerThomas GasserManu SharmaAlexis Elbaznull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
Using MR, our findings provide further support for a causal relationship between dairy intake and higher PD risk, not biased by confounding or reverse causation. Further studies are needed to elucidate the underlying mechanisms. © 2022 International Parkinson and Movement Disorder Society.