Remifentanil but not sufentanil induces cardioprotection in human ischemic heart muscle in vitro.

Marcin KuneckiTomasz OleksyJan MartynówMichalina ZygmuntMarek DejaTomasz KargulJolanta BiernatPiotr PodolecKrzysztof S GołbaWojciech Płazak

Published in: BMC pharmacology & toxicology (2023)

Remifentanil, but not sufentanil, induces a cardioprotective effect on human right atria muscle in in vitro conditions, manifested as the increased amplitude of their contraction during reperfusion after 60 min of ischemia.

Keyphrases

endothelial cells
skeletal muscle
induced pluripotent stem cells
acute myocardial infarction
cerebral ischemia
atrial fibrillation
blood brain barrier
subarachnoid hemorrhage
ischemia reperfusion injury